Optimizing Lambda Schedules for Alchemical Free Energy Calculations

XXX1, YYY1, and Darrin M. York1
1Laboratory for Biomolecular Simulation Research, Institute for Quantitative Biomedicine and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA

Learning objectives

  • Use FFPOPT to Run Dihedral Scans for a Simple Molecule

  • Use FFPOPT with a Machine Learning Potential to Fit New Dihedral Parameters

Relevant literature

  • Coming Soon!

Tutorial

Optimizing Lambda Schedules